Dr Rosemary Waring found that most people with autism conditions have a deficiency in a key detoxification pathway. The pathway involves using sulfur in the form of sulfate (known as sulfation). The enzyme involved is phenol sulfur-transferase (PST), but the problem is thought to hinge on an inadequate supply of usable sulfate ions, not the metabolic enzyme itself. First Part What are Epsom salts and how do they work? Epsom salts are magnesium sulfate. Salts are just molecules that form because the parts have opposite electrical charges that bind together. Magnesium has a positive charge. Sulfate has a negative charge, and performs all sorts of unique biological functions. The two elements dissociate in solution (English translation: break apart and separate in liquid). Epsom salts are available at most local grocers or health food stores, or inexpensively in bulk at agricultural supply stores.
Here are several methods for giving Epsom salts. The ratio is not exact, just what seems to get the salts dissolved and on the skin. Epsom salt baths – Most people use about one to two cups per tub. Dissolve the salts in hot water first and then fill the tub to about waist deep, as warm as possible. The amount of salts you may find works best will depend on the individual tolerance, the temperature of the water, and the size of the tub. The warmer the water and larger the tub, the more salts will dissolve. If you see negative reactions, such as irritability or hyperactivity, then decrease the amount of salts. You may need to start with as little as one tablespoon of salts, and work up gradually. Epsom salts baths are very calming for most people. This works well just before bedtime. Most guides say to soak for about 20 minutes or more. It is okay to let the salts dry on the skin. You may notice a dry clear-white powder. If it is too itchy or irritating, just rinse it off. If the skin feels too dry, use lotion or oils to moisturize. Diarrhea or loose stools may result if children drink the bath water. Spray – Mix one part salts and one part water (add more water if the salts are not dissolved) and put in a spray-squirt bottle. Mist the person’s chest and/or back and let it dry on the skin. This method works well in the summer. Footbath – Mix one part salts to two parts water (or more so the salts dissolve) and let the person soak their feet in it. My boys would soak their feet about 30 minutes while they did reading or homework. Homemade lotion – This is my favorite at the moment. Cheap and easy. Recipe 1 from Karen D: Heat some Epsom salts with a little water to dissolve them. I put about one teaspoon of water in three tablespoons of salts and microwave for a minute or so. Add more water if necessary. Then mix this into around four ounces of any lotion or cream you like. I have used suntan lotion, handcream, cocoa butter, body lotion, aloe vera cream, whatever I find that is on sale or inexpensive without the chemicals I am trying to avoid. This seems to work better if the cream or lotion is water-based rather than oil-based. Good buys are at the local grocer in the lotion section. Apply to skin anywhere as often as desired. Some new commercially prepared Epsom salt creams are available but can be very expensive and may contain chemicals that are not tolerated. Recipe 2 from Rubby: Well – my recipe for the Epsom salt cream is quite unscientific. I don't really measure my ingredients – I just add a bit of everything until I have the consistency I like. Ingredients: I start by adding the salt into the hot water and boiling it for a few minures (make sure the salt is dissolved), then I add the Petroleum jelly and mix it all with a hand mixer (one you would use to whipp cream); once I get a white, creamy mixture, I add some cocoa butter cream and mix again.And that's it. I get approximately 250 – 350 ml cream. I use it only once a day, on days when we don't do a bath. I use it to massage my daughter's back, her chest and her legs (with a focus on her feet – she loves it). Somethimes, I add in a few drops of Lavander Oil. The cost – minimal. I buy my local pharmacy brand (in Toronto – Shoppers Drug Mart – "Life") Petroleum Jelly (500 gr.) $3 (CAD), Coca Butter Cream (400 ml) $3 and Epsom Salt (1kg) $3.5 (CAD). I think that the two creams I use will make at least 3 Epsom salt mixtures, which means that my cream costs me approximately $2-3 (CAD). And it lasts me a long time – even though I try to put on my daughter as much as possible. Epsom salt oil – Neither of my sons nor I liked the salty film left on the skin after a bath (felt itchy). I mixed some coconut oil in with the salts and water. Actually, it is more oil than water. Three tablespoons water plus four tablespoons salts plus 12 tablespoons coconut oil. The coconut oil is good for the skin anyway and it seems to counter the drying effect of the salts. I found that just mixing the salts and oil did not dissolve the salts, so I needed to add some water. I apply this liberally on the skin and it soaks in plus leaves the skin smooth and soft. Adjust the quantity of salts to your liking. Sponge – A solution of one part salts to four parts water works well. Dampen a sponge in the mixture and apply to any part of the body. Poultice or skin patch – You can mix some Epsom salts and whatever kind of lotion the person can tolerate into a paste. Put this paste on a large bandaid and apply to the skin. The salts will soak into the skin.
High phenolic foods, chemical additives, and enzymes Phenols and salicylates do not occur in the same intensity in all foods. Those parents on the Feingold diet point out some studies rank foods by the quantity of phenols present in a food as very low, low, medium, high, and very high. These are not absolute values or correspond with exact toxicities or reactions to the foods. Rather it is included only as a guide. The Feingold literature also notes that salicylates are cumulative in the body, and may only be processed out at a certain rate. So, if you consume more than the body can process out, you get a reaction. The exact reason No-Fenol helps is not precisely understood. The phenol metabolism, sulfation, and detoxification issues are rather complex. It may not be due so much to the presence of phenols as to the specific structure of these phenols. The research literature indicates that some phenolic compounds are modified by the addition of carbohydrate groups to their structures, which may inhibit their crossing into cells and being metabolized properly. A current hypothesis for why No-Fenol helps may be because the enzymes in this product are able to remove certain carbohydrate groups from the phenols, or otherwise modify their structure, thus allowing normal processing by the detoxification pathways. Many parents giving these enzymes have said how wonderful it is to be able to give even a low amount of phenols again. Just being able to add foods containing a little bit of fruit greatly expands their child’s menu. Enzymes may help protect against hidden sources of the unwanted phenol compounds. Sometimes a food may appear to give a 'phenolic' or unwanted reaction. It may be because the food actually contains a phenolic-based preservative. At times this turns out to be the case with dairy. Vitamin A palmitate is often added to low-fat or skim milks. The palmitate may be preserved with a phenolic compound. When people switch to a whole milk or milk product without this preservative (or artifical colorings/flavorings) they no longer have a problem with dairy. The same may be true of commercial breads. Often the shortening or pan sprays used in baked goods contain artificial preservatives that are the cause of the problem and not the grains in themselves. This may be the same with other foods as well.
Which enzyme products to not contain fruit-derived enzymes? Enzymes in general can be great! However, a particular person may not tolerate certain fillers, added herbs, particular enzyme ingredient, or even a particular blend. The fruit-derived enzymes are perfectly fine enzymes which are well-studied and work great for many people. But it is also know that the can be a problem for those that are phenol sensitive, salicylate sensitive, or have detoxification problems. If you are not sensitive to fruit-derived enzymes, the fruit-derived enzymes are not a problem. If you are having difficulting tolerating enzymes, check to see if it contains fruit-derived enzymes. If so, try a product without the fruit-derived enzymes...not many out there but there are some good choices. Personally, I like Lacto as a starter enzyme, particularly if you have problems with dairy or serious gut injury. But just about any product without the fruit-derived enzymes may work...just start at a lower dose and gradually increase the amount to higher doses over the course of 4-5 days. After a little gut healing, higher levels of proteases aren't a problem and you can switch around to other products, or add more enzymes in, if you want. Here is a list of what the products without fruit-derived enzymes I are aware of. Please note that even if a product does not have fruity-derived enzymes, you still need to check to see if it fits your needs or purpose. If anyone knows of other products without fruit-derived enzymes, please let me know and I'll add it to this reference list: Enzymedica (the Thera-blends do not contain fruit-derived enzymes):
Houston Nutraceuticals:
Klaire Labs:
Kirkman:
Pure Essence:
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This independent site is for education and information about digestive enzymes. There is a large need to provide practical and general information on enzyme therapy for a wide range of uses. Enzymes have been around a very long time. Hopefully this site will help reduce the learning curve. Ideas, comments, and questions are welcome. ![]() |
